PetriKey

Virus

Zika virus

Aedes flavivirus, congenital microcephaly

ZEE-kuh VY-rus

flavivirusarbovirusmosquito-borneaedescongenitalrna-virus

High-yield clue

Aedes flavivirus classically linked to congenital microcephaly, and it can also spread sexually and across the placenta.

Overview

A positive-sense single-stranded RNA flavivirus spread mainly by Aedes mosquitoes but also by sexual and vertical (mother-to-fetus) routes, studied for its link to congenital malformations.

Classification

  • Flaviviridae
  • Genus Orthoflavivirus
  • Positive-sense ssRNA
  • Enveloped
  • Arbovirus

Lab & identification clues

  • RNA detection (NAAT) vocabulary
  • Flavivirus serologic cross-reactivity concept
  • Neurotropism study framing

Associations

  • Aedes vector plus sexual and vertical transmission
  • Congenital Zika syndrome and microcephaly vocabulary
  • Guillain-Barre syndrome association
  • Explosive outbreak epidemiology

Commonly confused with

  • Dengue virus
  • Rubella virus

Your notes

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundationssourceNCBI Bookshelf: Medical Microbiology organism chapterssourceCDC: CDC disease and public-health topic pagessource