Virus
Dengue virus
Aedes-borne flavivirus, breakbone fever
DEN-gay VY-rus
High-yield clue
Aedes-transmitted flavivirus with four serotypes (DENV 1-4); a prior infection with one serotype can worsen a later infection through antibody-dependent enhancement.
Overview
An enveloped positive-sense single-stranded RNA flavivirus (genus Orthoflavivirus) spread by Aedes mosquitoes, studied as the classic four-serotype arbovirus with antibody-dependent enhancement on second infection.
Classification
- Flaviviridae
- Genus Orthoflavivirus
- Positive-sense ssRNA
- Enveloped
- Icosahedral capsid
Lab & identification clues
- NS1 antigen detection vocabulary
- Serotype-specific (DENV 1-4) framing
- Thrombocytopenia study association
Associations
- Aedes aegypti and Aedes albopictus vector
- 'Breakbone fever' severe joint and muscle pain vocabulary
- Antibody-dependent enhancement on secondary infection
- Tropical and subtropical epidemiology
Commonly confused with
- Chikungunya virus
- Zika virus
Your notes
Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.