PetriKey

Bacterium

Viridans streptococci

Alpha-hemolytic optochin-resistant oral strep

VIR-ih-danz strep-tuh-KOK-eye

Gram positivegram-positivecoccialpha-hemolyticendocarditisoral-flora

High-yield clue

Alpha-hemolytic, optochin-resistant, and bile-insoluble, they seed subacute endocarditis on damaged valves after dental procedures cause transient bacteremia.

Overview

A heterogeneous group of alpha-hemolytic oral streptococci (including S. sanguinis, S. mitis, S. mutans) that are normal mouth flora. They are the classic teaching cause of subacute bacterial endocarditis on previously damaged valves.

Classification

  • Gram-positive
  • Cocci in chains
  • Alpha-hemolytic
  • Optochin-resistant
  • No Lancefield group antigen

Lab & identification clues

  • Alpha-hemolytic (green) colonies
  • Optochin-resistant (pneumococcus is sensitive)
  • Bile-insoluble (pneumococcus is soluble)
  • No capsule

Associations

  • Subacute bacterial endocarditis
  • Transient bacteremia after dental work
  • Members: S. sanguinis, S. mitis, S. mutans

Commonly confused with

  • Streptococcus pneumoniae
  • Enterococcus species

Your notes

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundationssourceNCBI Bookshelf: Medical Microbiology organism chapterssourceCDC: CDC disease and public-health topic pagessource