Disease
Viral hepatitis overview
Hepatitis A-E: routes and chronicity
hep-uh-TYE-tis
High-yield clue
Jaundice with high transaminases; A and E are fecal-oral and acute, while B, C, and D are bloodborne and can become chronic.
Overview
An umbrella of liver inflammation from hepatitis viruses A through E, studied for contrasting transmission routes, chronicity risk, and cross-dependencies such as HDV needing HBV.
Classification
- Viral liver inflammation syndrome
- Hepatitis viruses A-E
- Acute vs chronic patterns
- Transaminase (ALT/AST) elevation
Lab & identification clues
- Elevated ALT/AST with jaundice vocabulary
- Hepatitis serology panels (HBsAg, anti-HCV)
- Fecal-oral (A, E) vs bloodborne (B, C, D) route contrast
Associations
- A and E: contaminated food/water, usually self-limited
- B, C, D: blood, sexual, and perinatal spread with chronic risk
- HDV requires HBV coinfection or superinfection
- Chronic B/C link to cirrhosis and hepatocellular carcinoma
Commonly confused with
- Alcoholic hepatitis
- EBV/CMV hepatitis
- Leptospirosis (Weil syndrome)
Your notes
Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.