PetriKey

Virus

Poliovirus

Enterovirus of paralytic poliomyelitis

POH-lee-oh-VY-rus

rna-viruspicornavirusenterovirusnon-envelopedfecal-oralvaccine

High-yield clue

Fecal-oral enterovirus that can destroy anterior horn motor neurons and cause asymmetric flaccid paralysis is the core clue.

Overview

A small non-enveloped positive-sense RNA enterovirus that spreads fecal-orally and, in a minority of infections, targets anterior horn motor neurons to cause flaccid paralysis; a landmark vaccine-preventable disease.

Classification

  • RNA virus
  • Positive-sense single-stranded RNA
  • Non-enveloped icosahedral
  • Family Picornaviridae, Enterovirus C

Lab & identification clues

  • Enterovirus classification concept
  • Stool and CSF detection vocabulary
  • Three serotype framing
  • Anterior horn motor-neuron tropism concept

Associations

  • Poliomyelitis with asymmetric flaccid paralysis
  • Fecal-oral transmission epidemiology
  • IPV (inactivated) vs OPV (oral live) vaccine history
  • Global eradication effort framing

Commonly confused with

  • Coxsackievirus
  • Enterovirus D68

Your notes

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundationssourceNCBI Bookshelf: Medical Microbiology organism chapterssourceCDC: CDC disease and public-health topic pagessource