PetriKey

Virus

Hepatitis E virus

Waterborne enteric hepatitis, risk in pregnancy

hep-uh-TY-tis EE VY-rus

rna-virusnon-envelopedfecal-oralwaterbornezoonosishepatitis

High-yield clue

Enterically transmitted hepatitis with high mortality risk in pregnant patients is the core study clue.

Overview

A small non-enveloped positive-sense RNA virus spread mainly by contaminated water that causes acute hepatitis and is studied for its unusually high fatality vocabulary in pregnancy.

Classification

  • RNA virus
  • Positive-sense single-stranded RNA
  • Non-enveloped
  • Family Hepeviridae, genus Paslahepevirus

Lab & identification clues

  • Anti-HEV IgM serology concept
  • RNA detection vocabulary
  • Multiple genotype framing (1-4 human)
  • Self-limited acute course vocabulary

Associations

  • Fecal-oral and waterborne transmission
  • Large epidemics in resource-limited settings (genotypes 1/2)
  • Zoonotic sporadic cases from pigs/game (genotypes 3/4)
  • Severe outcomes in pregnancy epidemiology

Commonly confused with

  • Hepatitis A virus
  • Hepatitis D virus

Your notes

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundationssourceNCBI Bookshelf: Medical Microbiology organism chapterssourceCDC: CDC disease and public-health topic pagessource