PetriKey

Antimicrobial

Fluoroquinolones

DNA gyrase/topoisomerase concept

floor-oh-KWIN-oh-lones

antimicrobialdnagyrasetopoisomeraseresistance

High-yield clue

DNA gyrase/topoisomerase target + resistance mutation vocabulary.

Overview

An antimicrobial class concept used to teach bacterial DNA gyrase/topoisomerase targeting and mutation-mediated resistance vocabulary.

Classification

  • Antimicrobial class
  • DNA replication concept

Lab & identification clues

  • Susceptibility vocabulary
  • Target mutation concept
  • Efflux resistance concept

Associations

  • Gram-negative rod study associations
  • Respiratory fluoroquinolone vocabulary
  • Resistance mechanism drills

Commonly confused with

  • Rifamycins
  • Beta-lactams

Your notes

Original mechanism summary for microbiology study. Sources checked: CDC antimicrobial-resistance guidance, NCBI Bookshelf Medical Microbiology, and standard coursework frameworks; reviewed 2026-06. Covers class, mechanism, and resistance vocabulary only; no prescribing, dosing, or patient-specific treatment guidance.

CDC: CDC antimicrobial resistance overview and threat reportssourceWHO: WHO bacterial priority pathogens list 2024sourceNCBI Bookshelf: Medical Microbiology antimicrobial mechanism foundationssource