PetriKey

Bacterium

Actinomyces israelii

Sulfur-granule filamentous anaerobe

ak-tin-oh-MY-seez iz-RAY-lee-eye

Gram positivegram-positivefilamentousanaerobebranchingoral-flora

High-yield clue

Yellow 'sulfur granules' draining from sinus tracts and cervicofacial 'lumpy jaw' after dental trauma are the core clues; unlike Nocardia it is anaerobic and not acid-fast.

Overview

A branching, filamentous Gram-positive anaerobe of the oral cavity that causes chronic draining sinus-tract infection. It is the classic non-acid-fast counterpart to Nocardia in coursework.

Classification

  • Gram-positive
  • Branching filamentous rod
  • Anaerobe
  • Not acid-fast

Lab & identification clues

  • Sulfur granules (yellow filament colonies)
  • Branching filaments on Gram stain
  • Anaerobic growth
  • Not acid-fast (contrast with Nocardia)

Associations

  • Cervicofacial 'lumpy jaw'
  • Dental trauma / poor oral hygiene
  • IUD-associated pelvic study association

Commonly confused with

  • Nocardia species
  • Fungal hyphae

Your notes

Original student-study summary. Sources checked: OpenStax Microbiology 2e, NCBI Bookshelf Medical Microbiology, and CDC topic pages where applicable; reviewed 2026-06. Educational only; no diagnosis, treatment, dosing, or specimen-handling guidance.

OpenStax: Microbiology 2e organism classification foundationssourceNCBI Bookshelf: Medical Microbiology organism chapterssourceCDC: CDC disease and public-health topic pagessource